1st Cup
The second angel delivered first cup of God's horror.
The second Angel preaches the fall of Babylon (Revelation 16:17-21 and Revelation 18:1-24)
Babylon means the gate of god and was founded by Nimrod.
A literal Babylon, which will be destroyed under the seventh vial.
Also read Revelation 16:17-21; 18:1-24
Background Reading:
Revelation 14:8
The Second Angel
8 A second angel followed and said, "Fallen! Fallen is Babylon the Great, which made all the nations drink the maddening wine of her adulteries."